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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TKTL2
All Species:
30.3
Human Site:
Y142
Identified Species:
60.61
UniProt:
Q9H0I9
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H0I9
NP_115512.3
626
67877
Y142
G
M
A
Y
T
G
K
Y
L
D
K
A
S
Y
R
Chimpanzee
Pan troglodytes
Q5R1W6
623
67821
Y141
G
M
A
Y
T
G
K
Y
F
D
K
A
S
Y
R
Rhesus Macaque
Macaca mulatta
XP_001095403
703
76522
Y219
G
M
A
Y
T
G
K
Y
L
D
K
A
S
Y
R
Dog
Lupus familis
XP_538204
596
64805
L138
E
G
S
V
W
E
A
L
A
F
A
S
H
Y
N
Cat
Felis silvestris
Mouse
Mus musculus
Q9D4D4
627
68429
Y143
G
M
A
Y
T
G
K
Y
F
D
K
A
S
Y
R
Rat
Rattus norvegicus
P50137
623
67625
Y141
G
M
A
Y
T
G
K
Y
F
D
K
A
S
Y
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508404
725
77819
Y243
G
M
A
Y
T
G
K
Y
F
D
K
A
S
Y
R
Chicken
Gallus gallus
XP_414333
627
68436
F141
G
M
A
Y
T
G
K
F
F
D
R
A
S
Y
R
Frog
Xenopus laevis
NP_001079885
625
67433
Y141
G
M
A
Y
T
G
K
Y
F
D
K
A
S
Y
R
Zebra Danio
Brachydanio rerio
NP_932336
625
67820
Y140
G
M
A
Y
T
G
K
Y
L
D
K
S
S
Y
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_623357
627
67899
N141
G
M
A
Y
V
G
K
N
F
D
K
A
N
Y
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P23254
680
73787
G143
A
A
T
Y
N
K
P
G
F
T
L
S
D
N
Y
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
66.1
85.9
75.4
N.A.
80.5
66.1
N.A.
56.8
66.5
72
69.3
N.A.
N.A.
60.1
N.A.
N.A.
Protein Similarity:
100
79.5
86.7
83
N.A.
89.4
79.5
N.A.
69
80.5
84.8
83.3
N.A.
N.A.
75.5
N.A.
N.A.
P-Site Identity:
100
93.3
100
6.6
N.A.
93.3
93.3
N.A.
93.3
80
93.3
93.3
N.A.
N.A.
73.3
N.A.
N.A.
P-Site Similarity:
100
93.3
100
20
N.A.
93.3
93.3
N.A.
93.3
93.3
93.3
100
N.A.
N.A.
80
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
43
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
9
84
0
0
0
9
0
9
0
9
75
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
84
0
0
9
0
0
% D
% Glu:
9
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
9
67
9
0
0
0
0
0
% F
% Gly:
84
9
0
0
0
84
0
9
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
9
84
0
0
0
75
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
9
25
0
9
0
0
0
0
% L
% Met:
0
84
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
9
0
0
9
0
0
0
0
9
9
9
% N
% Pro:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
84
% R
% Ser:
0
0
9
0
0
0
0
0
0
0
0
25
75
0
0
% S
% Thr:
0
0
9
0
75
0
0
0
0
9
0
0
0
0
0
% T
% Val:
0
0
0
9
9
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
92
0
0
0
67
0
0
0
0
0
92
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _